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Viral vectors have been the favored delivery vehicle for gene therapy, and adeno-associated virus has become a candidate of great interest because of its biological properties which include site specific integration in human chromosome 19. In this volume methods of vector production and use in in vitro and in vivo experiments are described, including recent studies with hematopoietic stem cells and non-dividing cells. Various protocols for preparing recombinant AAV vectors and their intracellular delivery are extensively discussed. The first trial of AAV as vector for human gene therapy was conducted in late 1995. |
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| Author(s) : | Format : Hardback Book |
| ISBN-10 : 3540610766 | ISBN-13 : 9783540610762 |
| RRP : £67.00 | Best available price : £ / $ |
| Prices as of : BST check live prices | |
Series Title : Current Topics in Microbiology & Immunology
Country Publication : Germany
Publication Date : 01/08/1996
Publisher : Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Page Length : ix,173mm
Page Size : 240mm