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Imaging in Drug Discovery and Early Clinical Trials by Markus Rudin
Describes the contribution of imaging modalities to the various stages of drug discovery and development, from early target validation to their use in clinical development programs. This title provides an overview on the role of imaging in drug discovery, and discusses major trends both with regard to technologies and applications.In this monograph the contribution of imaging modalities to the various stages of drug discovery and development, from early target validation to their use in clinical development programs, is described. Chapters are devoted to the description of the drug discovery process as such, to the various imaging modalities being used both preclinically and clinically, to applications of imaging during the optimization of a lead compound (addressing issues such as bioavailability and efficacy) and during the drug safety evaluation. A chapter describes imaging biomarkers, their development, advantages and the potential pitfalls associated with their use. In the translation of imaging tools from animals to man regulatory issues have to be addressed, which are dealt with in a separate section. The monograph provides a comprehensive overview on the role of imaging in drug discovery today and discusses major developments and trends both with regard to technologies and applications. |
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| Author(s) : Markus Rudin | Format : Hardback Book |
| ISBN-10 : 3764371579 | ISBN-13 : 9783764371579 |
| RRP : £144.50 | Best available price : £ / $ |
| Prices as of : BST check live prices | |
Product Details:
Series Title : Progress in Drug Research S.
Country Publication : Switzerland
Publication Date : 01/05/2005
Publisher : Birkhauser Verlag AG
Page Length : X, 392mm
Page Size : 241mm