Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy by Toshiwo Andoh & Masao Oguro & Hideo Ikeda

Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy Based on conference proceedings held in Japan, this book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents.

This volume is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistence, inhibitors of mammalian DNA topoisomerases and drug resistence, and preclinical studies of DNA topoisomerases.
Author(s) : Toshiwo Andoh Format : Hardback Book
ISBN-10 : 0849349702 ISBN-13 : 9780849349706
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Product Details:

Country Publication : United States

Publication Date : 01/12/1992

Publisher : Taylor & Francis Ltd

Page Length : 400mm

Page Size : 250mm